CP-640186 hydrochloride

Modify Date: 2025-08-25 20:27:38

CP-640186 hydrochloride structure	Common Name	CP-640186 hydrochloride
	CAS Number	591778-70-0	Molecular Weight	522.078
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₆ClN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CP-640186 hydrochloride

CP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.

Name	9-Anthryl[(3R)-3-(4-morpholinylcarbonyl)-1,4'-bipiperidin-1'-yl]methanone hydrochloride (1:1)
Synonym	More Synonyms

Description	CP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Acetyl-CoA Carboxylase Research Areas >> Metabolic Disease
References	[1]. Harwood HJ Jr, et al. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. J Biol Chem. 2003 Sep 26;278(39):37099-111. [2]. Yamashita T, et al. Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6314-8.

Description

CP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Acetyl-CoA Carboxylase

Research Areas >> Metabolic Disease

References

[1]. Harwood HJ Jr, et al. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. J Biol Chem. 2003 Sep 26;278(39):37099-111.

[2]. Yamashita T, et al. Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6314-8.

Molecular Formula	C₃₀H₃₆ClN₃O₃
Molecular Weight	522.078
Exact Mass	521.244507
Storage condition	2-8℃

9-Anthryl[(3R)-3-(4-morpholinylcarbonyl)-1,4'-bipiperidin-1'-yl]methanone hydrochloride (1:1)

Methanone, 9-anthracenyl[(3R)-3-(4-morpholinylcarbonyl)[1,4'-bipiperidin]-1'-yl]-, hydrochloride (1:1)

CP-640186 hydrochloride

CP-640186 (hydrochloride)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CP-640186(hydrochloride)
Price: Check
Purity: 99.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: CP-640186 hydrochloride
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: CP-640186 hydrochloride
Price: $650.0/100mg $1200.0/250mg $2500.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CP-640186 (hydrochloride)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: $138/10mM*1mLinDMSO

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CP-640186 hydrochloride

Use of CP-640186 hydrochloride

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CP-640186 hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

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