H-Val-Pro-Pro-OH
Modify Date: 2025-08-25 18:46:19
H-Val-Pro-Pro-OH structure
|
Common Name | H-Val-Pro-Pro-OH | ||
|---|---|---|---|---|
| CAS Number | 58872-39-2 | Molecular Weight | 311.38 | |
| Density | 1.275 g/cm3 | Boiling Point | 566.446ºC at 760 mmHg | |
| Molecular Formula | C15H25N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 296.376ºC | |
Use of H-Val-Pro-Pro-OHH-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. |
| Name | (2S)-1-[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 9 μM (ACE)[1]. |
| In Vitro | H-Val-Pro-Pro-OH, a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM[1]. H-Val-Pro-Pro-OH could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes[2]. |
| References |
| Density | 1.275 g/cm3 |
|---|---|
| Boiling Point | 566.446ºC at 760 mmHg |
| Molecular Formula | C15H25N3O4 |
| Molecular Weight | 311.38 |
| Flash Point | 296.376ºC |
| Exact Mass | 311.18500 |
| PSA | 103.94000 |
| LogP | 0.61240 |
| Storage condition | 2-8℃ |
| Val-pro-pro |
| V-P-P |
| L-valyl-L-prolyl-L-proline |
| L-Proline,L-valyl-L-prolyl |
| L-Val-L-Pro-L-Pro |
| H-VAL-PRO-PRO-OH |