H-Ile-Pro-Pro-OH

Modify Date: 2024-01-02 18:30:06

H-Ile-Pro-Pro-OH structure	Common Name	H-Ile-Pro-Pro-OH
	CAS Number	26001-32-1	Molecular Weight	325.40
	Density	1.248 g/cm3	Boiling Point	572.556ºC at 760 mmHg
	Molecular Formula	C₁₆H₂₇N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	300.071ºC

Use of H-Ile-Pro-Pro-OH

H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].

Name	h-ile-pro-pro-oh
Synonym	More Synonyms

Description	H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Target	IC50: 5 μM (ACE)[2]
In Vitro	Vitro: Ile-Pro-Pro (IPP) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)[1].
In Vivo	Vivo: Ile-Pro-Pro attenuates arterial dysfunction in L-NAME-treated rats[1] Ile-Pro-Pro (IPP) decreases blood pressure in spontaneously hypertensive rats (SHR) [1]. Ile-Pro-Pro (IPP) attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice[1].
References	[1]. Nonaka A, et al. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertens Res. 2014 Aug;37(8):703-7. [2]. Nakamura Y, et al. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci. 1995 Apr;78(4):777-83.

Density	1.248 g/cm3
Boiling Point	572.556ºC at 760 mmHg
Molecular Formula	C₁₆H₂₇N₃O₄
Molecular Weight	325.40
Flash Point	300.071ºC
Exact Mass	325.20000
PSA	103.94000
LogP	1.00250

isoleucyl-prolyl-proline

IPP,ACE-I Inhibitor

Ile-Pro-Pro

GL Biochem (Shanghai) Ltd.
China
Product Name: H-Ile-Pro-Pro-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

DC Chemicals Limited
China
Product Name: H-Ile-Pro-Pro-OH
Price: $350.0/100mg $700.0/250mg $1400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Nanjing Peptide Biotech Ltd
China
Product Name: H-Ile-Pro-Pro-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: H-ILE-PRO-PRO-OH
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: H-Ile-Pro-Pro-OH
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

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Price: ￥800/10 mg

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H-Ile-Pro-Pro-OH

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