Mono-Pt

Modify Date: 2024-01-14 15:07:27

Mono-Pt Structure
Mono-Pt structure
Common Name Mono-Pt
CAS Number 587832-29-9 Molecular Weight 605.01
Density N/A Boiling Point N/A
Molecular Formula C19H24ClN3O3PtS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mono-Pt


Mono-Pt is the first platinum(II) complex that inhibits cancer cells through a non-DNA-binding mitophagy pathway. Mono-Pt promotes the occurrence of mitophagy in cancer cells via stimulating endoplasmic reticulum stress (ERS) and activating unfolded protein response (UPR)[1].

 Names

Name Mono-Pt

 Mono-Pt Biological Activity

Description Mono-Pt is the first platinum(II) complex that inhibits cancer cells through a non-DNA-binding mitophagy pathway. Mono-Pt promotes the occurrence of mitophagy in cancer cells via stimulating endoplasmic reticulum stress (ERS) and activating unfolded protein response (UPR)[1].
Related Catalog
References

[1]. Guo Y, et al. DNA-Unresponsive Platinum(II) Complex Induces ERS-Mediated Mitophagy in Cancer Cells. J Med Chem. 2022;65(1):520-530.

 Chemical & Physical Properties

Molecular Formula C19H24ClN3O3PtS
Molecular Weight 605.01