Mono-Pt

Names

[ Name ]:
Mono-Pt

Biological Activity

[Description]:

Mono-Pt is the first platinum(II) complex that inhibits cancer cells through a non-DNA-binding mitophagy pathway. Mono-Pt promotes the occurrence of mitophagy in cancer cells via stimulating endoplasmic reticulum stress (ERS) and activating unfolded protein response (UPR)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Mitophagy

[References]

[1]. Guo Y, et al. DNA-Unresponsive Platinum(II) Complex Induces ERS-Mediated Mitophagy in Cancer Cells. J Med Chem. 2022;65(1):520-530.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₄ClN₃O₃PtS

[ Molecular Weight ]:
605.01

Mono-Pt

Names

Biological Activity

Chemical & Physical Properties

Related Compounds