587832-29-9

587832-29-9 structure

Name: Mono-Pt
Chemical Name: Mono-Pt
CAS Number: 587832-29-9
Molecular Formula: C₁₉H₂₄ClN₃O₃PtS
Molecular Weight: 605.01
Catalog: Research Areas Cancer
Create Date: 2022-04-09 07:03:05
Modify Date: 2024-01-14 15:07:27
Mono-Pt is the first platinum(II) complex that inhibits cancer cells through a non-DNA-binding mitophagy pathway. Mono-Pt promotes the occurrence of mitophagy in cancer cells via stimulating endoplasmic reticulum stress (ERS) and activating unfolded protein response (UPR)[1].

Name	Mono-Pt

Description	Mono-Pt is the first platinum(II) complex that inhibits cancer cells through a non-DNA-binding mitophagy pathway. Mono-Pt promotes the occurrence of mitophagy in cancer cells via stimulating endoplasmic reticulum stress (ERS) and activating unfolded protein response (UPR)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Mitophagy
References	[1]. Guo Y, et al. DNA-Unresponsive Platinum(II) Complex Induces ERS-Mediated Mitophagy in Cancer Cells. J Med Chem. 2022;65(1):520-530.

Molecular Formula	C₁₉H₂₄ClN₃O₃PtS
Molecular Weight	605.01