1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL

Modify Date: 2024-01-19 09:42:39

1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL Structure
1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL structure
Common Name 1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL
CAS Number 5741-22-0 Molecular Weight 239.31
Density 1.054g/cm3 Boiling Point 379.2ºC at 760mmHg
Molecular Formula C13H21NO3 Melting Point N/A
MSDS N/A Flash Point 183.2ºC

 Use of 1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL


Moprolol ((±)-Moprolol) is an beta-adrenergic receptor blocker, which can be used for research in essential hypertension[1][2][3].

 Names

Name moprolol

  Biological Activity

Description Moprolol ((±)-Moprolol) is an beta-adrenergic receptor blocker, which can be used for research in essential hypertension[1][2][3].
Related Catalog
Target

Beta-1 adrenergic receptor

In Vitro l-Moprolol 是一种 β 阻断剂的 l-对映体,具有低负性肌力活性和轻度内在拟交感神经活性,可有效用于全身性高血压研究。在原发性开角型青光眼 (POAG) 或高眼压 (OHT) 模型中,局部应用l-Moprolol 可与噻洛尔一样有效地降低眼压 (IOP),由于其对支气管肌肉缺乏活性,已成为抑制青光眼的一种很有前景的化合物[3]。
References

[1]. Borowiecki P, et al. Development of a novel chemoenzymatic route to enantiomerically enriched β-adrenolytic agents. A case study toward propranolol, alprenolol, pindolol, carazolol, moprolol, and metoprolol. RSC Adv. 2022 Aug 10;12(34):22150-22160.  

[2]. Liu J, et al. beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension. Clin Pharmacol Ther. 2006 Jul;80(1):23-32.  

[3]. Rossetti L, et al. The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension. Graefes Arch Clin Exp Ophthalmol. 1994 Nov;232(11):670-4.  

 Chemical & Physical Properties

Density 1.054g/cm3
Boiling Point 379.2ºC at 760mmHg
Molecular Formula C13H21NO3
Molecular Weight 239.31
Flash Point 183.2ºC
Exact Mass 239.15200
PSA 50.72000
LogP 1.82380
Index of Refraction 1.509

 Precursor & DownStream

Precursor  1

DownStream  0