Butoxamine hydrochloride

Modify Date: 2025-08-25 19:01:06

Butoxamine hydrochloride Structure
Butoxamine hydrochloride structure
Common Name Butoxamine hydrochloride
CAS Number 5696-15-1 Molecular Weight 303.82500
Density N/A Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H26ClNO3 Melting Point N/A
MSDS Chinese USA Flash Point 190.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Butoxamine hydrochloride


Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1].

 Names

Name 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol,hydrochloride
Synonym More Synonyms

 Butoxamine hydrochloride Biological Activity

Description Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1].
Related Catalog
Target

Beta-2 adrenergic receptor

In Vivo Butaxamine hydrochloride(25 μg/kg/min、50 μg/kg/min、100 μg/kg/min,15 分钟;静脉注射)提高了乙醇麻醉、水利尿大鼠的尿量水平[1]。
References

[1]. Shibouta Y, et al. Antidiuresis induced by beta1- and beta2-adrenergic agonists in ethanol-anesthetized rats. Eur J Pharmacol. 1978 Jan 15;47(2):149-57.  

 Chemical & Physical Properties

Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H26ClNO3
Molecular Weight 303.82500
Flash Point 190.3ºC
Exact Mass 303.16000
PSA 50.72000
LogP 3.70670
InChIKey URPAECSKKQLCII-UHFFFAOYSA-N
SMILES COc1ccc(OC)c(C(O)C(C)NC(C)(C)C)c1.Cl

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22-36
Safety Phrases 26
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles25

More Articles
Restoration of neutrophil immunocompetence after cardiopulmonary bypass by beta-adrenergic blockers.

Surgery 147(4) , 562-74, (2010)

To evaluate the possible protective effect of sympatholytic medications with respect to neutrophil function, we evaluated the influence of a nonselective beta-blocker medication on the interaction of ...

Does selective beta-1 blockade provide bone marrow protection after trauma/hemorrhagic shock?

Surgery 152(3) , 322-30, (2012)

Previously, nonselective beta-blockade (BB) with propranolol demonstrated protection of the bone marrow (BM) after trauma and hemorrhagic shock (HS). Because selective beta-1 blockers are used commonl...

Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.

Psychoneuroendocrinology 33(10) , 1411-8, (2008)

Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion and social withdrawal. While these clinical symptoms are well characterized, the mechanism of their cause is...

 Synonyms

N-tert.-Butyl-pseudomethoxaminhydrochlorid
BUTOXAMINE HYDROCHLORIDE
Butoxamine hydrochloride (USAN)
BW 64-9
Butoxamine HCl
N-tert-Butylmethoxamine hydrochloride
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