Picloxydine

Modify Date: 2024-01-08 18:56:24

Picloxydine structure	Common Name	Picloxydine
	CAS Number	5636-92-0	Molecular Weight	475.37800
	Density	1.5g/cm3	Boiling Point	703.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₄Cl₂N₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	379.5ºC

Use of Picloxydine

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

Name	picloxydine

Description	Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
Target	Bacterial[1]
In Vivo	0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms[1]. Picloxydine is also used in eye drops in the topical therapy of trachoma[2].
References	[1]. Newcomb GM, et al. An in vivo comparison of chlorhexidine and picloxydine mouthrinses: a possible association between chemical structure and antiplaque activity. J Periodontol. 1977 May;48(5):282-4. [2]. Obikili AG, et al. A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma. Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1988;65(3-4):119-32.

Density	1.5g/cm3
Boiling Point	703.8ºC at 760 mmHg
Molecular Formula	C₂₀H₂₄Cl₂N₁₀
Molecular Weight	475.37800
Flash Point	379.5ºC
Exact Mass	474.15600
PSA	150.00000
LogP	4.25580
Index of Refraction	1.717
Storage condition	2-8℃