CGP 13501

Modify Date: 2025-08-27 10:06:06

Use of CGP 13501

CGP13501 is a positive allosteric modulator of GABAB receptor. CGP13501 is a structural analogue of propofol[1].

Name	3-(3,5-di-tert-butyl-4-hydroxyphenyl)-2,2-dimethyl-propionaldehyde

Description	CGP13501 is a positive allosteric modulator of GABAB receptor. CGP13501 is a structural analogue of propofol[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	GABAB receptor[1]
References	[1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001 Nov;60(5):963-71.

Density	0.965g/cm3
Boiling Point	344.8ºC at 760 mmHg
Molecular Formula	C₁₉H₃₀O₂
Molecular Weight	290.44
Flash Point	146.8ºC
Exact Mass	290.22500
PSA	37.30000
LogP	4.75480
Index of Refraction	1.499
InChIKey	XGWATTXMMMANFJ-UHFFFAOYSA-N
SMILES	CC(C)(C=O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

WGK Germany	3

Phenol,2,6-bis(...

CAS#:87-97-8

Isobutyraldehyde

CAS#:78-84-2

CGP 13501

CAS#:56189-68-5

2,6-Di-tert-but...

CAS#:128-39-2

CGP 13501

CAS#:56189-68-5

Precursor 3
CAS#:87-97-8 Phenol,2,6-bis(... CAS#:78-84-2 Isobutyraldehyde CAS#:128-39-2 2,6-Di-tert-but...
DownStream 1
CAS#:57717-80-3 CGP 7930