PRRSV/CD163-IN-1
Modify Date: 2024-04-03 09:10:59
PRRSV/CD163-IN-1 structure
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Common Name | PRRSV/CD163-IN-1 | ||
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| CAS Number | 560995-89-3 | Molecular Weight | 557.62 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H24FN5O5S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PRRSV/CD163-IN-1PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) [1]. |
| Name | PRRSV/CD163-IN-1 |
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| Description | PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) [1]. |
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| Related Catalog | |
| In Vitro | PRRSV/CD163-IN-1 (Compound B7) (5 μM) 抑制 PRRSV GP4 糖蛋白和 CD163-SRCR5 结构域之间的蛋白间相互作用 (PPI)[1]。 PRRSV/CD163-IN-1 (24 h) 在浓度低于 25μM 时可被 PAMs 良好耐受，LC50 值为 81.7 μM[1]。< br/>PRRSV/CD163-IN-1 (0, 5, 10, 15, or 20 μM; 4 h) 以剂量依赖性方式抑制 PRRSV 感染 PAMs[1]。 PRRSV/CD163-IN-1 (15 μM) 显着抑制由 I 型和 II 型 PRRSV 菌株引起的感染[1]。 RT-PCR[1] Cell Line: Porcine alveolar macrophages (PAMs) Concentration: 0, 5, 10, 15, or 20 μM Incubation Time: 4 h Result: Revealed a dose-dependent inhibition of PRRSV infection of PAMs. |
| References |
| Molecular Formula | C25H24FN5O5S2 |
|---|---|
| Molecular Weight | 557.62 |