Cephalonium

Modify Date: 2024-01-02 20:08:05

Cephalonium structure	Common Name	Cephalonium
	CAS Number	5575-21-3	Molecular Weight	458.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈N₄O₅S₂	Melting Point	147-150° (dec)
	MSDS	Chinese USA	Flash Point	N/A

Use of Cephalonium

Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci[1][2][3].

Name	(6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonym	More Synonyms

Description	Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci[1][2][3].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	β-lactam
References	[1]. Harada K, et, al. Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis. Antibiotics (Basel). 2020 Apr 21;9(4):197. [2]. Demon D, et, al. The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. Vet Microbiol. 2012 Nov 9;160(1-2):141-50. [3]. Berry EA, et, al. Effect of an intramammary teat seal and dry cow antibiotic in relation to dry period length on postpartum mastitis. J Dairy Sci. 2007 Feb;90(2):760-5.

Melting Point	147-150° (dec)
Molecular Formula	C₂₀H₁₈N₄O₅S₂
Molecular Weight	458.51
Exact Mass	458.07200
PSA	190.05000
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU2800000

CHEMICAL NAME :: Pyridinium, 4-carbamoyl-1-((2-carboxy-8-oxo-7-(2-(2-thienyl)aceta mido)-5-thia-1-aza- bicyclo(4.2.0)oct-2-en-3-yl)methyl)- hydroxide, inner salt

CAS REGISTRY NUMBER :: 5575-21-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H18-N4-O5-S2

MOLECULAR WEIGHT :: 458.54

WISWESSER LINE NOTATION :: T46 ANV ES GUTJ HVQ CMV1- BT5SJ& G1- AT6KJ DVZ &Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971

Hazard Codes	Xn

Cephalonium

Cefalonum

Cefalonio [INN-Spanish]

Cefalonium [INN-Latin]

Cefalonium Hydrate

CEFALONIUM

EINECS 226-948-7

DC Chemicals Limited
China
Product Name: Cefalonium (anhydrous)
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Cephalonium
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Cephalonium

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Cephalonium Biological Activity

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CHEMICAL IDENTIFICATION

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ACUTE TOXICITY DATA

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