Phytosphingosine

Modify Date: 2024-01-03 16:40:13

Phytosphingosine Structure
Phytosphingosine structure
Common Name Phytosphingosine
CAS Number 554-62-1 Molecular Weight 317.507
Density 1.0±0.1 g/cm3 Boiling Point 483.7±40.0 °C at 760 mmHg
Molecular Formula C18H39NO3 Melting Point 102ºC
MSDS USA Flash Point 246.4±27.3 °C

 Use of Phytosphingosine


Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells[1].

 Names

Name phytosphingosine
Synonym More Synonyms

 Phytosphingosine Biological Activity

Description Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells[1].
Related Catalog
References

[1]. Moon-Taek Park, et al. Phytosphingosine Induces Apoptotic Cell Death via Caspase 8 Activation and Bax Translocation in Human Cancer Cells. Clin Cancer Res. 2003 Feb;9(2):878-85.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 483.7±40.0 °C at 760 mmHg
Melting Point 102ºC
Molecular Formula C18H39NO3
Molecular Weight 317.507
Flash Point 246.4±27.3 °C
Exact Mass 317.292999
PSA 86.71000
LogP 5.18
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.490

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 1.0

 Synthetic Route

 Articles61

More Articles
14-3-3-regulated Ca(2+)-dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis.

Cell Death Differ. 20(2) , 209-17, (2013)

In eukaryotic cells, sphingoid long chain bases (LCBs) such as sphingosine or phytosphingosine (PHS) behave as second messengers involved in various processes including programmed cell death (PCD). In...

Detection of water-soluble disease-associated PrP species in blood and brain of scrapie-infected hamster.

Arch. Virol. 160 , 2219-29, (2015)

The high-speed supernatant (S(HS)) of scrapie-infected hamster brain homogenate contains a soluble infectivity similar to that of the plasma that escapes leukodepletion and can transmit prion infectio...

Morphogenesis checkpoint kinase Swe1 is the executor of lipolysis-dependent cell-cycle progression.

Proc. Natl. Acad. Sci. U. S. A. 112(10) , E1077-85, (2015)

Cell growth and division requires the precise duplication of cellular DNA content but also of membranes and organelles. Knowledge about the cell-cycle-dependent regulation of membrane and storage lipi...

 Synonyms

(2S,3S,4R)-2-Aminooctadecane-1,3,4-triol
Phytosphingosine
(4R,3S,2S)-2-aminooctadecane-1,3,4-triol
PHYTOSPHINGOSINE HYDROCHLORIDE
4-HYDROXYSPHINGANINE
4D-Hydroxysphinganine
1,3,4-Octadecanetriol, 2-amino-, (2S,3S,4R)-
(4R)-4-Hydroxysphinganine
(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol
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