4-Hydroxyisoleucine

Modify Date: 2025-08-25 18:20:28

4-Hydroxyisoleucine Structure
4-Hydroxyisoleucine structure
Common Name 4-Hydroxyisoleucine
CAS Number 55399-93-4 Molecular Weight 147.172
Density 1.2±0.1 g/cm3 Boiling Point 331.6±32.0 °C at 760 mmHg
Molecular Formula C6H13NO3 Melting Point 223-224℃
MSDS N/A Flash Point 154.4±25.1 °C

 Use of 4-Hydroxyisoleucine


(2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound isolated from Trigonella foenum-graecum, with anti-diabetes and anti-diabetic nephropathy activity[1].

 Names

Name (4S)-4-hydroxy-L-isoleucine
Synonym More Synonyms

 4-Hydroxyisoleucine Biological Activity

Description (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound isolated from Trigonella foenum-graecum, with anti-diabetes and anti-diabetic nephropathy activity[1].
Related Catalog
References

[1]. Shi X, et al. Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers. Sci Rep. 2017 Oct 20;7(1):13703.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 331.6±32.0 °C at 760 mmHg
Melting Point 223-224℃
Molecular Formula C6H13NO3
Molecular Weight 147.172
Flash Point 154.4±25.1 °C
Exact Mass 147.089539
PSA 83.55000
LogP -0.44
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.496
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26
HS Code 1302199099

 Synthetic Route

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

4-Hydroxyisoleucine
ent-gabosine F
L-erythro-Pentonic acid, 2-amino-2,3,5-trideoxy-3-methyl-, (4ξ)-
(2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid
2,3,4-Trihydroxy-6-methylcyclohexanone
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