Sarcophine

Modify Date: 2024-01-13 15:47:01

Sarcophine structure	Common Name	Sarcophine
	CAS Number	55038-27-2	Molecular Weight	316.43500
	Density	1.08g/cm3	Boiling Point	472.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	203.5ºC

Use of Sarcophine

Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum[1].

Name	Sarcophine
Synonym	More Synonyms

Description	Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum[1].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	Sarcophine ((+)-Sarcophine) 是一种重组甘氨酸受体抑制剂，Ki 值为 2.1 μM[1]。 Sarcophine (1-100 mM; 24 h) 对 HEK293 细胞具有细胞毒性，LD50 值为 29.3 mM[1]。
References	[1]. Saleh HA, et, al. Sarcophine and (7S, 8R)-dihydroxydeepoxysarcophine from the Red Sea soft coral Sarcophyton glaucum as in vitro and in vivo modulators of glycine receptors. Neurotoxicology. 2020 Sep;80:105-111.

Density	1.08g/cm3
Boiling Point	472.8ºC at 760 mmHg
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.43500
Flash Point	203.5ºC
Exact Mass	316.20400
PSA	38.83000
LogP	4.63260
Index of Refraction	1.536

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RR1108000

CHEMICAL NAME :: Oxireno(9,10)cyclotetradeca(1,2-b)furan-9(1ah)-one, 2,3,6,7,10a,13,14,14a-octahydro- 1a,5,8,12-tetramethyl-, (1aS-(1aR*,4E,10aR*,11E,14aR*))-

CAS REGISTRY NUMBER :: 55038-27-2

LAST UPDATED :: 198903

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H28-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 12,593,1974

N/A

CAS#:65817-46-1

~82%

Sarcophine

CAS#:55038-27-2

Literature: Frincke, James M.; McIntyre, Douglas E.; Faulkner, John D. Tetrahedron Letters, 1980 , vol. 21, p. 735 - 738

N/A

CAS#:65817-46-1

(1aS,4E,11E,14a...

CAS#:74740-97-9

Sarcophine

CAS#:55038-27-2

N/A

CAS#:137762-26-6

Detail

Literature: Kobayashi, Masaru Journal of Chemical Research, Miniprint, 1991 , # 11 p. 2840 - 2852

Oxireno(9,10)cyclotetradeca(1,2-B)furan-9(1ah)-one,2,3,6,7,10A,13,14,14A-octahydro-1A,5,8,12-tetramethyl-(van) (9ci)

(1aS,4E,10aS,11E,14aS)-2,3,6,7,10a,13,14,14a-Octahydro-1a,5,8,12-tetramethyloxireno[9,10]cyclotetradeca[1,2-b]furan-9(1aH)-one

Sarcophyne

Sarcophin

Oxireno(9,10)cyclotetradeca(1,2-B)furan-9(1ah)-one,2,3,6,7,10A,13,14,14A-octahydro-1A,5,8,12-tetramethyl-,(1as-(1ar*,4E,10ar*,11E,14ar*))

Sarcophin a

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sarcophine
Price: Check
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Sarcophine
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
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DC Chemicals Limited
China
Product Name: Sarcophine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
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Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sarcophin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Sarcophine

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