8-Hydroxymethyl guanosine

Modify Date: 2025-09-10 18:29:11

8-Hydroxymethyl guanosine structure	Common Name	8-Hydroxymethyl guanosine
	CAS Number	54898-41-8	Molecular Weight	313.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₅N₅O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 8-Hydroxymethyl guanosine

8-Hydroxymethyl guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	8-(hydroxymethyl)guanosine
Synonym	More Synonyms

Description	8-Hydroxymethyl guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [2]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

[2]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₁₁H₁₅N₅O₆
Molecular Weight	313.27
Exact Mass	313.10200
PSA	179.74000

8-hydroxymethylguanosine

8-hydroxymethyl-guanosine

8-(Hydroxymethyl)guanosin

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8-Hydroxymethyl guanosine

Use of 8-Hydroxymethyl guanosine

Names

8-Hydroxymethyl guanosine Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.