Irigenin
Modify Date: 2025-08-20 18:14:46
Irigenin structure
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Common Name | Irigenin | ||
|---|---|---|---|---|
| CAS Number | 548-76-5 | Molecular Weight | 360.31500 | |
| Density | 1.461g/cm3 | Boiling Point | 646.1ºC at 760mmHg | |
| Molecular Formula | C18H16O8 | Melting Point | 189-192ºC | |
| MSDS | N/A | Flash Point | 237.7ºC | |
Use of IrigeninIrigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1]. |
| Name | irigenin |
|---|---|
| Synonym | More Synonyms |
| Description | Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1]. |
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| Related Catalog | |
| In Vitro | Irigenin specifically targets α9β1 and α4β1 integrin binding sites on Extra Domain A (EDA) comprising LEU46, PHE47, PRO48, GLU58, LEU59 and GLN60 in its C-C loop. Irigenin binds to the C-C loop of EDA, thereby blocking its interaction with integrins on the cell surface and thus abrogating subsequent Epithelial-Mesenchymal transition[1]. |
| References |
| Density | 1.461g/cm3 |
|---|---|
| Boiling Point | 646.1ºC at 760mmHg |
| Melting Point | 189-192ºC |
| Molecular Formula | C18H16O8 |
| Molecular Weight | 360.31500 |
| Flash Point | 237.7ºC |
| Exact Mass | 360.08500 |
| PSA | 118.59000 |
| LogP | 2.60260 |
| Index of Refraction | 1.649 |
| InChIKey | TUGWPJJTQNLKCL-UHFFFAOYSA-N |
| SMILES | COc1cc(-c2coc3cc(O)c(OC)c(O)c3c2=O)cc(O)c1OC |
| Storage condition | 2-8C |
| HS Code | 2914509090 |
|---|
| Precursor 0 | |
|---|---|
| DownStream 2 | |
CAS#:64-18-6
CAS#:487-71-8| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
| 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one |
| 7,5,3'-Trihydroxy-6,4',5'-trimethoxyisoflavon |
| 5,7,3'-trihydroxy-6,4',5'-trimethoxyisoflavone |
| Irigenin |
| EINECS 208-958-3 |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Irigenin
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Irigenin
- Price: ￥968.0/20mg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Irigenin
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Irigenin
- Price: $500.0/100mg $900.0/250mg $1800.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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Price: ￥800/5 mg
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