Nek2/Hec1-IN-2

Modify Date: 2024-04-03 10:57:06

Nek2/Hec1-IN-2 Structure
Nek2/Hec1-IN-2 structure
Common Name Nek2/Hec1-IN-2
CAS Number 544416-00-4 Molecular Weight 310.37
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H14N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nek2/Hec1-IN-2


Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].

 Names

Name WAY-324546
Synonym More Synonyms

 Nek2/Hec1-IN-2 Biological Activity

Description Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].
Related Catalog
Target

Nek2/Hec1[1]

References

[1]. Qiu XL, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52(6):1757-67.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C16H14N4OS
Molecular Weight 310.37
Exact Mass 310.088837
LogP 3.57
Index of Refraction 1.668
InChIKey GANRESSEAJEWSH-UHFFFAOYSA-N
SMILES Cc1ccc(-c2csc(NC(=O)c3cnccn3)n2)c(C)c1

 Synonyms

MFCD03376422
2-Pyrazinecarboxamide, N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]-2-pyrazinecarboxamide
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