544416-00-4

544416-00-4 structure
544416-00-4 structure
  • Name: Nek2/Hec1-IN-2
  • Chemical Name: WAY-324546
  • CAS Number: 544416-00-4
  • Molecular Formula: C16H14N4OS
  • Molecular Weight: 310.37
  • Catalog: Research Areas Cancer
  • Create Date: 2022-12-04 18:27:03
  • Modify Date: 2024-04-03 10:57:06
  • Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].

Name WAY-324546
Synonyms MFCD03376422
2-Pyrazinecarboxamide, N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]-2-pyrazinecarboxamide
Description Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].
Related Catalog
Target

Nek2/Hec1[1]

References

[1]. Qiu XL, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52(6):1757-67.  

Density 1.3±0.1 g/cm3
Molecular Formula C16H14N4OS
Molecular Weight 310.37
Exact Mass 310.088837
LogP 3.57
Index of Refraction 1.668
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