Fenbendazole sulfone

Modify Date: 2024-01-11 14:58:12

Fenbendazole sulfone Structure
Fenbendazole sulfone structure
Common Name Fenbendazole sulfone
CAS Number 54029-20-8 Molecular Weight 331.34600
Density 1.486 g/cm3 Boiling Point N/A
Molecular Formula C15H13N3O4S Melting Point >300ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Fenbendazole sulfone


Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent[1][2].

 Names

Name Fenbendazole Sulfone
Synonym More Synonyms

 Fenbendazole sulfone Biological Activity

Description Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent[1][2].
Related Catalog
References

[1]. M B Petersen, et al. Pharmacokinetics of Fenbendazole Following Intravenous and Oral Administration to Pigs. Am J Vet Res. 2000 May;61(5):573-6.

[2]. David L Brandon, et al. Analysis of Fenbendazole Residues in Bovine Milk by ELISA. J Agric Food Chem. 2002 Oct 9;50(21):5791-6.

 Chemical & Physical Properties

Density 1.486 g/cm3
Melting Point >300ºC
Molecular Formula C15H13N3O4S
Molecular Weight 331.34600
Exact Mass 331.06300
PSA 109.53000
LogP 3.72780
Index of Refraction 1.68
Storage condition -20°C Freezer

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H317
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
Risk Phrases 22-38
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport

 Articles4

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J. Agric. Food Chem. 64 , 356-63, (2016)

A novel nickel oxide nanoparticle-deposited silica (SiO2@NiO) composite was prepared via liquid-phase deposition (LPD) and then employed as a solid-phase extraction (SPE) sorbent. When the SPE was cou...

Pharmacokinetics of oxfendazole in sheep.

Am. J. Vet. Res. 42(7) , 1143-5, (1981)

Pharmacokinetics of oxfendazole and its sulfone metabolite were determined in 6 sheep. Oxfendazole achieved mean peak plasma concentrations of 0.76 micrograms/ml at 30 hours after oral administration ...

A high performance liquid chromatographic method for the determination of febantel and its major metabolites in lamb plasma.

Biomed. Chromatogr. 7(2) , 78-81, (1993)

A high performance liquid chromatographic (HPLC) method for the determination of the anthelminthic pro-benzimidazole febantel and its major metabolites in lamb plasma has been developed. Samples were ...

 Synonyms

fenbendazole sulfone