1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
Modify Date: 2024-01-06 16:25:47
![1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one Structure](https://www.chemsrc.com/caspic/400/53948-10-0.png)
1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one structure
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Common Name | 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one | ||
|---|---|---|---|---|
| CAS Number | 53948-10-0 | Molecular Weight | 309.316 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 462.8±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H15NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 233.7±28.7 °C | |
Use of 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-oneAristolactam BIII is a potent DYRK1A inhibitor and inhibits the kinase activity of DYRK1A in vitro (IC50= 9.67 nM. Aristolactam BIII rescues the proliferative defects of DYRK1A transgenic (TG) mouse-derived fibroblasts and neurological and phenotypic defects of DS-like Drosophila models[1]. |
| Name | 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one |
|---|---|
| Synonym | More Synonyms |
| Description | Aristolactam BIII is a potent DYRK1A inhibitor and inhibits the kinase activity of DYRK1A in vitro (IC50= 9.67 nM. Aristolactam BIII rescues the proliferative defects of DYRK1A transgenic (TG) mouse-derived fibroblasts and neurological and phenotypic defects of DS-like Drosophila models[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 462.8±45.0 °C at 760 mmHg |
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.316 |
| Flash Point | 233.7±28.7 °C |
| Exact Mass | 309.100098 |
| PSA | 60.28000 |
| LogP | 3.23 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.681 |
| HS Code | 2933990090 |
|---|
|
~80%
1,2,9-Trimethox... CAS#:53948-10-0 |
| Literature: Choi, Young Lok; Kim, Joa Kyum; Choi, Sang-Un; Min, Yong-Ki; Bae, Myung-Ae; Kim, Bum Tae; Heo, Jung-Nyoung Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 3036 - 3040 |
|
~36%
1,2,9-Trimethox... CAS#:53948-10-0 |
| Literature: Estevez, Juan C.; Estevez, Ramon J.; Castedo, Luis Tetrahedron, 1995 , vol. 51, # 39 p. 10801 - 10810 |
|
~%
1,2,9-Trimethox... CAS#:53948-10-0 |
| Literature: Estevez; Guitian; Villaverde; Castedo Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5785 - 5786 |
|
~%
1,2,9-Trimethox... CAS#:53948-10-0 |
| Literature: Estevez; Guitian; Villaverde; Castedo Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5785 - 5786 |
|
~%
1,2,9-Trimethox... CAS#:53948-10-0 |
| Literature: Estevez; Guitian; Villaverde; Castedo Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5785 - 5786 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Dibenz[cd,f]indol-4(5H)-one, 1,2,9-trimethoxy- |
| 3,4,6-trimethoxyaristolactame |
| aristolactam A II |
| Aristololactam B III |
| 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one |
| aristololactam A-II |
| Dibenz(cd,f)indol-4(5H)-one,2-hydroxy-1-methoxy |
| aristolactam BIII |
- BioBioPha
- China
- Product Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- Price: ￥3250.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- Price: ￥4418.0/5mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Aristolactam BIII
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: ARISTOLACTAM BIII
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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