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97399-91-2

97399-91-2 structure
97399-91-2 structure
  • Name: Aristolactam AIIIa
  • Chemical Name: Aristolactam AIIIa
  • CAS Number: 97399-91-2
  • Molecular Formula: C16H11NO4
  • Molecular Weight: 281.263
  • Catalog: Natural product Alkaloid
  • Create Date: 2016-10-26 04:38:03
  • Modify Date: 2024-01-10 19:24:42
  • Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells[1].

Name Aristolactam AIIIa
Synonyms 2,9-Dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one
Dibenz[cd,f]indol-4(5H)-one, 2,9-dihydroxy-1-methoxy-
Description Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells[1].
Related Catalog
References

[1]. Chia YC, et al. Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii. J Nat Prod. 2000 Aug;63(8):1160-3.  

Density 1.5±0.1 g/cm3
Boiling Point 521.1±50.0 °C at 760 mmHg
Molecular Formula C16H11NO4
Molecular Weight 281.263
Flash Point 268.9±30.1 °C
Exact Mass 281.068817
PSA 82.55000
LogP 1.62
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.812