1H-Imidazole-2-methanol,1-(phenylmethyl)-

Modify Date: 2024-01-08 05:04:28

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure
1H-Imidazole-2-methanol,1-(phenylmethyl)- structure
Common Name 1H-Imidazole-2-methanol,1-(phenylmethyl)-
CAS Number 5376-10-3 Molecular Weight 188.22600
Density 1.13 g/cm3 Boiling Point 354.9ºC at 760 mmHg
Molecular Formula C11H12N2O Melting Point 89-92ºC
MSDS USA Flash Point 168.4ºC

 Names

Name (1-Benzyl-1H-imidazol-2-yl)methanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.13 g/cm3
Boiling Point 354.9ºC at 760 mmHg
Melting Point 89-92ºC
Molecular Formula C11H12N2O
Molecular Weight 188.22600
Flash Point 168.4ºC
Exact Mass 188.09500
PSA 38.05000
LogP 1.42370
Index of Refraction 1.592

 MSDS

Name: (1-Benzyl-1h-imidazol-2-yl)methanol 97% Material Safety Data Sheet
Synonym: 1-Benzyl-2-(hydroxymethyl)imidazol
CAS: 5376-10-3
Section 1 - Chemical Product MSDS Name:(1-Benzyl-1h-imidazol-2-yl)methanol 97% Material Safety Data Sheet
Synonym:1-Benzyl-2-(hydroxymethyl)imidazol

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
5376-10-3 (1-Benzyl-1H-imidazol-2-yl)methanol, 9 97% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 5376-10-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: pleasant odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 89 - 92 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C11H12N2O
Molecular Weight: 188

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acid chlorides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 5376-10-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(1-Benzyl-1H-imidazol-2-yl)methanol, 97% - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 5376-10-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 5376-10-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 5376-10-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2933290090

 Synthetic Route

~92%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: Galons, Herve; Bergerat, Isabelle; Combet Farnoux, Claude; Miocque, Marcel Synthesis, 1982 , # 12 p. 1103 - 1105

~92%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: Kleyi, Phumelele; Walmsley, Ryan S.; Gundhla, Isaac Z.; Walmsley, Tara A.; Jauka, Tembisa I.; Dames, Joanna; Walker, Roderick B.; Torto, Nelson; Tshentu, Zenixole R. South African Journal of Chemistry, 2012 , vol. 65, p. 231 - 238

~%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: Journal of Medicinal Chemistry, , vol. 33, # 2 p. 781 - 789

~10%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Detail
Literature: Journal of Organic Chemistry, , vol. 54, # 6 p. 1256 - 1264

~%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: Journal of the American Chemical Society, , vol. 71, p. 383,384

~%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: Journal of the American Chemical Society, , vol. 71, p. 383,384

~%

1H-Imidazole-2-methanol,1-(phenylmethyl)- Structure

1H-Imidazole-2-...

CAS#:5376-10-3

Literature: South African Journal of Chemistry, , vol. 65, p. 231 - 238

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00174260
(1-benzylimidazol-2-yl)methanol