1,3-Dichloroacetone

Modify Date: 2024-01-02 23:41:02

1,3-Dichloroacetone structure	Common Name	1,3-Dichloroacetone
	CAS Number	534-07-6	Molecular Weight	126.969
	Density	1.3±0.1 g/cm3	Boiling Point	173.0±0.0 °C at 760 mmHg
	Molecular Formula	C₃H₄Cl₂O	Melting Point	43 °C
	MSDS	Chinese USA	Flash Point	89.4±0.0 °C
	Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Name	1,3-Dichloroacetone
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	173.0±0.0 °C at 760 mmHg
Melting Point	43 °C
Molecular Formula	C₃H₄Cl₂O
Molecular Weight	126.969
Flash Point	89.4±0.0 °C
Exact Mass	125.963921
PSA	17.07000
LogP	1.29
Vapour density	4.38 (vs air)
Vapour Pressure	1.3±0.3 mmHg at 25°C
Index of Refraction	1.437
Water Solubility	27.9 g/L (20 º C)

1,3-Dichloroacetone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC1430000

CHEMICAL NAME :: 2-Propanone, 1,3-dichloro-

CAS REGISTRY NUMBER :: 534-07-6

BEILSTEIN REFERENCE NO. :: 0605456

LAST UPDATED :: 199710

DATA ITEMS CITED :: 23

MOLECULAR FORMULA :: C3-H4-Cl2-O

MOLECULAR WEIGHT :: 126.97

WISWESSER LINE NOTATION :: G1V1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 29 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18900 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 27 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 53 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - iritis Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 720 mg/kg/90D-C

TOXIC EFFECTS :: Behavioral - fluid intake Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 37500 ug/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 2 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.05 mg/m3;Skin JAN 1993

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H300 + H310 + H330-H314-H341
Precautionary Statements	P260-P264-P280-P284-P301 + P310-P302 + P350
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;
Risk Phrases	R24;R26/28;R36/37/38;R68
Safety Phrases	S26-S36/37/39-S45-S28A-S1
RIDADR	UN 3286 3/PG 2
WGK Germany	3
RTECS	UC1430000
Packaging Group	II
Hazard Class	6.1
HS Code	29147090

Precursor 10
CAS#:816-39-7 1,3-Dibromo-2-p... CAS#:78-95-5 Chloroacetone CAS#:79-37-8 Oxalyl chloride CAS#:86-68-0 Quininic acid
CAS#:18107-18-1 (Trimethylsilyl... CAS#:68-12-2 N,N-Dimethylfor... CAS#:593-71-5 Chloroiodomethane CAS#:105-39-5 ethyl chloroacetate
CAS#:108-20-3 Isopropyl ether CAS#:20485-53-4 3-chloro-1-diaz...
DownStream 10
CAS#:57892-71-4 2-(chloromethyl... CAS#:54679-16-2 4-(chloromethyl... CAS#:30494-97-4 4-Chloromethyl-... CAS#:37781-33-2 3-Chloro-2-(chl...
CAS#:57892-76-9 2-(Chloromethyl... CAS#:3364-76-9 4-Chloromethyl-... CAS#:40516-57-2 4-(Chloromethyl... CAS#:4771-31-7 4-(Chloromethyl...
CAS#:41963-17-1 4-(Chloromethyl... CAS#:96-23-1 1,3-Dichloro-2-...

HS Code	2914700090
Summary	HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

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In vitro metabolism and bioactivation of 1,2,3-trichloropropane.

Toxicol. Appl. Pharmacol. 113(1) , 152-8, (1992)

In vitro studies using rat and human hepatic microsomes have shown that the halogenated hydrocarbon 1,2,3-trichloropropane (TCP) is bioactivated to the direct acting mutagen 1,3-dichloroacetone (DCA)....

Effects of pH and temperature on the degradation of chloroacetones that are mutagenic.

Bull. Environ. Contam. Toxicol. 39(3) , 549-54, (1987)

2-Propanone, 1,3-dichloro-

1,3-Dichloropropan-2-one

MFCD00000937

1,3-Dichloroacetone

monochloromethyl ketone

1,3-dichloropropanone

EINECS 208-585-6

4,4'-Dimethoxystilbendichlorid

1,3-dichloro acetone

1,3-dichloro-2-propanone

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1,3-Dichloroacetone
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,3-Dichloroacetone
Price: ￥418.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,3-dichloroacetone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 1,3-Dichloroacetone
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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1,3-Dichloroacetone

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