aflatoxin Q1

Modify Date: 2024-01-24 10:19:18

aflatoxin Q1 Structure
aflatoxin Q1 structure
Common Name aflatoxin Q1
CAS Number 52819-96-2 Molecular Weight 328.27
Density N/A Boiling Point N/A
Molecular Formula C17H12O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of aflatoxin Q1


Aflatoxin Q1 is a hydroxy metabolite of Aflatoxin B1 (AFB1), which is a mycotoxin produced by Aspergillus flavus (A. flavus). Aflatoxin Q1, as well as and aflatoxin B1 8,9-oxide, is the major oxidative products formed from aflatoxin B1 in human liver microsomes, at all substrate concentrations. the 3 alpha-hydroxylation of aflatoxin B1 to aflatoxin Q1 is a potentially significant detoxication pathway[1][2].

 Names

Name aflatoxin Q1
Synonym More Synonyms

 aflatoxin Q1 Biological Activity

Description Aflatoxin Q1 is a hydroxy metabolite of Aflatoxin B1 (AFB1), which is a mycotoxin produced by Aspergillus flavus (A. flavus). Aflatoxin Q1, as well as and aflatoxin B1 8,9-oxide, is the major oxidative products formed from aflatoxin B1 in human liver microsomes, at all substrate concentrations. the 3 alpha-hydroxylation of aflatoxin B1 to aflatoxin Q1 is a potentially significant detoxication pathway[1][2].
Related Catalog
References

[1]. Raney KD, et al. Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1. Chem Res Toxicol. 1992 Mar-Apr;5(2):202-10.  

[2]. Yamada M, et al. Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4. J Microbiol Biotechnol. 2020 Aug 28;30(8):1207-1213.  

 Chemical & Physical Properties

Molecular Formula C17H12O7
Molecular Weight 328.27
Exact Mass 328.05800
PSA 95.20000
LogP 1.76740

 Safety Information

RIDADR UN 3172

 Synonyms

Aflatoxin Q1
3-hydroxy-Aflatoxin B1
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