| Name | Aflatoxin B1-13C17 solution |
|---|---|
| Synonyms | Fully 13C-labelled Aflatoxin B1 |
| Description | Aflatoxin B1-13C17 is 13C- and 15N-labeled Aflatoxin B1 (HY-N6615). Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
| References |
| Molecular Formula | 13C17H12O6 |
|---|---|
| Molecular Weight | 329.15 |
| Flash Point | 2℃ |
| Exact Mass | 329.12000 |
| PSA | 74.97000 |
| LogP | 2.27650 |
| Storage condition | ?20°C |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302 + H312 + H332-H319 |
| Precautionary Statements | P210-P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F,Xn |
| Risk Phrases | 11-20/21/22-36 |
| Safety Phrases | 16-36/37 |
| RIDADR | UN 1648 3 / PGII |