PSB 36
PSB 36 structure
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Common Name | PSB 36 | ||
|---|---|---|---|---|
| CAS Number | 524944-72-7 | Molecular Weight | 386.48800 | |
| Density | 1.304g/cm3 | Boiling Point | 646.008ºC at 760 mmHg | |
| Molecular Formula | C21H30N4O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 344.493ºC | |
Use of PSB 36PSB36 is a potent and selective antagonist of adenosine A1 receptor, with Kis 0.12 nM, 187 nM, 552 nM, 2300 nM, and 6500 nM for rA1, hA2B, rA2A, hA3 and rA3 receptors respectively. PSB36 can be used for the research of hyperalgesia[1][2]. |
| Name | psb 36 |
|---|---|
| Synonym | More Synonyms |
| Description | PSB36 is a potent and selective antagonist of adenosine A1 receptor, with Kis 0.12 nM, 187 nM, 552 nM, 2300 nM, and 6500 nM for rA1, hA2B, rA2A, hA3 and rA3 receptors respectively. PSB36 can be used for the research of hyperalgesia[1][2]. |
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| Related Catalog | |
| Target |
rA1:0.12 nM (Ki) hA2B:187 nM (Ki) rA2A:552 nM (Ki) hA3:2300 nM (Ki) rA3:6500 nM (Ki) |
| References |
| Density | 1.304g/cm3 |
|---|---|
| Boiling Point | 646.008ºC at 760 mmHg |
| Molecular Formula | C21H30N4O3 |
| Molecular Weight | 386.48800 |
| Flash Point | 344.493ºC |
| Exact Mass | 386.23200 |
| PSA | 92.91000 |
| LogP | 2.14650 |
| Index of Refraction | 1.616 |
| InChIKey | CIBIXJYFYPFMTN-UHFFFAOYSA-N |
| SMILES | CCCCn1c(=O)c2[nH]c(C34CC5CC(CC3C5)C4)nc2n(CCCO)c1=O |
| RIDADR | NONH for all modes of transport |
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Antinociceptive effects of novel A2B adenosine receptor antagonists.
J. Pharmacol. Exp. Ther. 308 , 358-366, (2004) Caffeine, an adenosine A1, A2A, and A2B receptor antagonist, is frequently used as an adjuvant analgesic in combination with nonsteroidal anti-inflammatory drugs or opioids. In this study, we have exa... |
| hms3268h03 |