Luteolin-3',7-di-O-glucoside

Modify Date: 2024-01-14 10:47:14

Luteolin-3',7-di-O-glucoside Structure
Luteolin-3',7-di-O-glucoside structure
Common Name Luteolin-3',7-di-O-glucoside
CAS Number 52187-80-1 Molecular Weight 610.51700
Density 1.742 g/cm3 Boiling Point 998ºC at 760 mmHg
Molecular Formula C27H30O16 Melting Point 220-250ºC
MSDS N/A Flash Point 330.2ºC

 Use of Luteolin-3',7-di-O-glucoside


Luteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].

 Names

Name 5-hydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym More Synonyms

 Luteolin-3',7-di-O-glucoside Biological Activity

Description Luteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].
Related Catalog
Target

ATCC and clinical strains of Ureaplasma urealyticum[3]

In Vitro Luteolin-3′,7-diglucoside (10 µM;24 h) 显著抑制在 45 % 低渗肝素缓冲溶液 (HBS) 中孵育 24 h 诱发的绵羊晶状体白内障[2]。 Luteolin-3′,7-diglucoside 抑制解脲支原体 ATCC 菌株的活性 (MIC=7.8-15.6 µM) 和解脲支原体临床菌株的活性 (MIC=0.48-1.95 µM)[3]。
References

[1]. Cristea D, et al. Identification and quantitative HPLC analysis of the main flavonoids present in weld (Reseda luteola L.)[J]. Dyes and Pigments, 2003, 57(3): 267-272.

[2]. Vit P, et al. Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model[J]. Journal of Health Science, 2008, 54(2): 196-202.

[3]. Bisignano C, et al. In Vitro Efficacy of Crataegus oxycantha L.(Hawthorn) and Its Major Components against ATCC and Clinical Strains of Ureaplasma urealyticum[J]. Advances in Microbiology, 2016, 6(12): 909-916.

 Chemical & Physical Properties

Density 1.742 g/cm3
Boiling Point 998ºC at 760 mmHg
Melting Point 220-250ºC
Molecular Formula C27H30O16
Molecular Weight 610.51700
Flash Point 330.2ºC
Exact Mass 610.15300
PSA 269.43000
Index of Refraction 1.727

 Synonyms

Luteolin-3',7-di-O-glucoside
EINECS 257-724-7