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Luteolin-3',7-di-O-glucoside

Names

[ CAS No. ]:
52187-80-1

[ Name ]:
Luteolin-3',7-di-O-glucoside

[Synonym ]:
Luteolin-3',7-di-O-glucoside
EINECS 257-724-7

Biological Activity

[Description]:

Luteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[Target]

ATCC and clinical strains of Ureaplasma urealyticum[3]


[In Vitro]

Luteolin-3′,7-diglucoside (10 µM；24 h) 显著抑制在 45 % 低渗肝素缓冲溶液 (HBS) 中孵育 24 h 诱发的绵羊晶状体白内障[2]。 Luteolin-3′,7-diglucoside 抑制解脲支原体 ATCC 菌株的活性 (MIC=7.8-15.6 µM) 和解脲支原体临床菌株的活性 (MIC=0.48-1.95 µM)[3]。

[References]

[1]. Cristea D, et al. Identification and quantitative HPLC analysis of the main flavonoids present in weld (Reseda luteola L.)[J]. Dyes and Pigments, 2003, 57(3): 267-272.

[2]. Vit P, et al. Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model[J]. Journal of Health Science, 2008, 54(2): 196-202.

[3]. Bisignano C, et al. In Vitro Efficacy of Crataegus oxycantha L.(Hawthorn) and Its Major Components against ATCC and Clinical Strains of Ureaplasma urealyticum[J]. Advances in Microbiology, 2016, 6(12): 909-916.

Chemical & Physical Properties

[ Density]:
1.742 g/cm3

[ Boiling Point ]:
998ºC at 760 mmHg

[ Melting Point ]:
220-250ºC

[ Molecular Formula ]:
C27H30O16

[ Molecular Weight ]:
610.51700

[ Flash Point ]:
330.2ºC

[ Exact Mass ]:
610.15300

[ PSA ]:
269.43000

[ Index of Refraction ]:
1.727

Related Compounds