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Kaempferol 3,7-di-O-glucoside

Names

[ CAS No. ]:
25615-14-9

[ Name ]:
Kaempferol 3,7-di-O-glucoside

[Synonym ]:
kaempferol 7-O-β-glucopyranosyl 3-O-β-glucopyranoside
kaempferol 3,7-O-β-D-diglucopyranoside
kaempferol-3,7-di-O-β-D-glucopyranoside
KAEMPFEROL-3,7-DI-O-GLUCOSIDE
kaempferol 3,7-di-O-β-D-glucopyranoside

Biological Activity

[Description]:

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[In Vitro]

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside; 0.1, 100 μM) has effective inhibition in Aβ1-42 fibril formation. Kaempferol-3,7-di-O-β-glucoside has less neurotoxicity on the cultured SH-SY5Y cells[1].

[References]

[1]. Pavithra Mettupalayam Kaliyannan Sundaramoorthy, et al. Extraction, isolation and identification of kaempferol 3,7 – Diglucoside in the leaf extracts of Evolvulus alsinoides (Linn.) and its inhibition potency against α-amylase, α-glucosidase, Acetylcholinesterase and amyloid aggregation. ORIGINAL ARTICLE, 2020,Volume : 16.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H30O16

[ Molecular Weight ]:
610.51700

[ Exact Mass ]:
610.15300

[ PSA ]:
269.43000

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds