Schaftoside

Modify Date: 2024-01-02 13:10:46

Schaftoside structure	Common Name	Schaftoside
	CAS Number	51938-32-0	Molecular Weight	564.49
	Density	1.8±0.1 g/cm3	Boiling Point	1028.2±65.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₂₈O₁₄	Melting Point	228ºC
	MSDS	Chinese USA	Flash Point	342.7±27.8 °C

Use of Schaftoside

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1].

Name	schaftoside
Synonym	More Synonyms

Description	Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Signaling Pathways >> Immunology/Inflammation >> MyD88 Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism Signaling Pathways >> Cytoskeleton >> Dynamin
In Vitro	Schaftoside inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Schaftoside also inhibits mRNA and protein expressions of proinflammatory cytokines(IL-1β, TNF-α, and IL-6)[1].
References	[1]. Zhou K, et al. Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells. J Pharmacol Sci. 2019 Jan;139(1):15-22.

Density	1.8±0.1 g/cm3
Boiling Point	1028.2±65.0 °C at 760 mmHg
Melting Point	228ºC
Molecular Formula	C₂₆H₂₈O₁₄
Molecular Weight	564.49
Flash Point	342.7±27.8 °C
Exact Mass	596.137756
PSA	269.43000
LogP	-3.06
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.754
Storage condition	2-8°C

Schaftoside MSDS(Chinese)

Safety Phrases	24/25
RIDADR	NONH for all modes of transport
RTECS	DJ2977250
HS Code	29389090

4H-1-Benzopyran-4-one, 8-(D-arabinopyranosyloxy)-6-(D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-

Shaftoside

Apigenin 8-C-|A-L-arabinoside 6-C-|A-D-glucoside

Schaftoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one

8-(D-Arabinopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl D-glucopyranoside

schaftozide

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Schaftoside
Price: ￥1478.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Schaftoside
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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