phosphoglycolohydroxamate

Modify Date: 2024-01-20 19:08:14

phosphoglycolohydroxamate Structure
phosphoglycolohydroxamate structure
Common Name phosphoglycolohydroxamate
CAS Number 51528-59-7 Molecular Weight 171.04600
Density 1.889g/cm3 Boiling Point N/A
Molecular Formula C2H6NO6P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of phosphoglycolohydroxamate


Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area[1][2].

 Names

Name phosphoglycolohydroxamic acid
Synonym More Synonyms

 phosphoglycolohydroxamate Biological Activity

Description Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area[1][2].
Related Catalog
Target

Aldolase, triose-phosphate isomerase[1]

In Vitro Phosphoglycolohydroxamic acid competitively inhibits rabbit muscle FDP-aldolase and chicken triosephosphate isomerase over a wide range pH[1].
References

[1]. By DENNIS J. LEWI, et al. Phosphoglycollohydroxamic Acid : an Inhibitor of Class I and I1 Aldolasesand Triosephosphate Isomerase. A Potential Antibacterial and Antifungal Agent. J. Chem. Soc., Chem. Commun., 1973, 713-715.

[2]. Sabine Gavalda, et al. N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5375-7.

 Chemical & Physical Properties

Density 1.889g/cm3
Molecular Formula C2H6NO6P
Molecular Weight 171.04600
Exact Mass 170.99300
PSA 129.39000
Index of Refraction 1.534

 Synonyms

1ik4
phosphoglycolohydroxamate
1tpw
1trd
[2-(hydroxyamino)-2-oxoethyl] dihydrogen phosphate
Phosphoglycolohydroxamic Acid
PGH
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