51528-59-7

51528-59-7 structure

Name: phosphoglycolohydroxamate
Chemical Name: phosphoglycolohydroxamic acid
CAS Number: 51528-59-7
Molecular Formula: C₂H₆NO₆P
Molecular Weight: 171.04600
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-08-23 14:49:33
Modify Date: 2024-01-20 19:08:14
Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area[1][2].

Name	phosphoglycolohydroxamic acid
Synonyms	1ik4 phosphoglycolohydroxamate 1tpw 1trd [2-(hydroxyamino)-2-oxoethyl] dihydrogen phosphate Phosphoglycolohydroxamic Acid PGH

Description	Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
Target	Aldolase, triose-phosphate isomerase[1]
In Vitro	Phosphoglycolohydroxamic acid competitively inhibits rabbit muscle FDP-aldolase and chicken triosephosphate isomerase over a wide range pH[1].
References	[1]. By DENNIS J. LEWI, et al. Phosphoglycollohydroxamic Acid : an Inhibitor of Class I and I1 Aldolasesand Triosephosphate Isomerase. A Potential Antibacterial and Antifungal Agent. J. Chem. Soc., Chem. Commun., 1973, 713-715. [2]. Sabine Gavalda, et al. N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5375-7.