Chlorobenzilate

Modify Date: 2024-01-03 15:50:36

Chlorobenzilate structure	Common Name	Chlorobenzilate
	CAS Number	510-15-6	Molecular Weight	325.187
	Density	1.3±0.1 g/cm3	Boiling Point	452.3±40.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₄Cl₂O₃	Melting Point	37ºC
	MSDS	Chinese USA	Flash Point	227.4±27.3 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

Name	chlorobenzilate
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	452.3±40.0 °C at 760 mmHg
Melting Point	37ºC
Molecular Formula	C₁₆H₁₄Cl₂O₃
Molecular Weight	325.187
Flash Point	227.4±27.3 °C
Exact Mass	324.032013
PSA	46.53000
LogP	4.73
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.588
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, alkalies, lime.

Chlorobenzilate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD2275000

CHEMICAL NAME :: Benzilic acid, 4,4'-dichloro-, ethyl ester

CAS REGISTRY NUMBER :: 510-15-6

BEILSTEIN REFERENCE NO. :: 2755859

LAST UPDATED :: 199701

DATA ITEMS CITED :: 32

MOLECULAR FORMULA :: C16-H14-Cl2-O3

MOLECULAR WEIGHT :: 325.20

WISWESSER LINE NOTATION :: GR DXQR DG&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 729 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 729 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/17W-I

TOXIC EFFECTS :: Immunological Including Allergic - decrease in cellular immune response

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5475 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 71 gm/kg/82W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - lymphoma, including Hodgkin's disease

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 gm/kg/83W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17520 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 72 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1752 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Endocrine - adrenal cortex tumors Skin and Appendages - tumors

TYPE OF TEST :: Morphological transformation

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 80 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12,85,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,73,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,73,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 56,107,1975 TOXICOLOGY REVIEW 85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971 Volume(issue)/page/year: 5,250,1970 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 13,231,1978 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H319-H410
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;N: Dangerous for the environment;
Risk Phrases	R22
Safety Phrases	S60-S61-S36/37-S24/25-S23-S53
RIDADR	UN 1593 6.1/PG 3
RTECS	DD2275000
HS Code	2918199090

4-Bromochlorobenzene

CAS#:106-39-8

Ethyl 2-(4-chlo...

CAS#:34966-48-8

Chlorobenzilate

CAS#:510-15-6

Literature: Levy, Amalia; Rakowitz, Amber; Mills, Nancy S. Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3990 - 3998

4-Bromochlorobenzene

CAS#:106-39-8

Chlorobenzilate

CAS#:510-15-6

Literature: Levy, Amalia; Rakowitz, Amber; Mills, Nancy S. Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3990 - 3998

4,4'-Dichloro benzil

CAS#:3457-46-3

Chlorobenzilate

CAS#:510-15-6

Literature: Voegtli; Laeuger Helvetica Chimica Acta, 1955 , vol. 38, p. 46,63

Ethanol

CAS#:64-17-5

4,4'-dichlorobe...

CAS#:23851-46-9

Chlorobenzilate

CAS#:510-15-6

Literature: Voegtli; Laeuger Helvetica Chimica Acta, 1955 , vol. 38, p. 46,63

Precursor 5
CAS#:106-39-8 4-Bromochlorobenzene CAS#:34966-48-8 Ethyl 2-(4-chlo... CAS#:3457-46-3 4,4'-Dichloro benzil CAS#:64-17-5 Ethanol
CAS#:23851-46-9 4,4'-dichlorobe...
DownStream 2
CAS#:23851-46-9 4,4'-dichlorobe... CAS#:34223-82-0 3,6-dichloroflu...

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Akar

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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Chlorobenzilate
Price: ￥978.0/100mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzeneacetic acid,4-chloro-a-(4-chlorophenyl)-a-hydroxy-, ethyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Chlorobenzilate

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