IRAK4-IN-16

Modify Date: 2024-01-31 21:09:13

IRAK4-IN-16 structure	Common Name	IRAK4-IN-16
	CAS Number	509093-72-5	Molecular Weight	478.519
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₅F₃N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IRAK4-IN-16

A potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively; inhibits IL-1 induced activation of NF-kB in primary human monocytes with IC50 of 0.3 uM, possesses excellent selectivity and pharmacokinetic properties.

Name	IRAK4-IN-16

Description	A potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively; inhibits IL-1 induced activation of NF-kB in primary human monocytes with IC50 of 0.3 uM, possesses excellent selectivity and pharmacokinetic properties.
References	References 1. Wang Z, et al. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5546-50. View Related Products by Target IRAK

Molecular Formula	C₂₇H₂₅F₃N₄O
Molecular Weight	478.519

DC Chemicals Limited
China
Product Name: IRAK4-IN-16
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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