CK7

Modify Date: 2025-08-25 11:50:28

CK7 Structure
CK7 structure
Common Name CK7
CAS Number 507487-89-0 Molecular Weight 328.34900
Density N/A Boiling Point N/A
Molecular Formula C14H12N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CK7


CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1].

 Names

Name 4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
Synonym More Synonyms

 CK7 Biological Activity

Description CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1].
Related Catalog
Target

CDK2

CDK9

References

[1]. Pilakowski J, et al. Design, synthesis and biological evaluation of novel aminopyrazole- and 7-azaindole-based Nek1 inhibitors and their effects on zebrafish kidney development. Bioorg Med Chem Lett. 2021;53:128418.

 Chemical & Physical Properties

Molecular Formula C14H12N6O2S
Molecular Weight 328.34900
Exact Mass 328.07400
PSA 151.51000
LogP 3.66880

 Synthetic Route

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CK7 Structure

CK7

CAS#:507487-89-0

Literature: Wang, Shudong; Meades, Christopher; Wood, Gavin; Osnowski, Andrew; Anderson, Sian; Yuill, Rhoda; Thomas, Mark; Mezna, Mokdad; Jackson, Wayne; Midgley, Carol; Griffiths, Gary; Fleming, Ian; Green, Simon; McNae, Iain; Wu, Su-Ying; McInnes, Campbell; Zheleva, Daniella; Walkinshaw, Malcolm D.; Fischer, Peter M. Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1662 - 1675

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CK7 Structure

CK7

CAS#:507487-89-0

Literature: Wang, Shudong; Midgley, Carol A.; Scaerou, Frederic; Grabarek, Joanna B.; Griffiths, Gary; Jackson, Wayne; Kontopidis, George; McClue, Steven J.; McInnes, Campbell; Meades, Christopher; Mezna, Mokdad; Plater, Andy; Stuart, Iain; Thomas, Mark P.; Wood, Gavin; Clarke, Rosemary G.; Blake, David G.; Zheleva, Daniella I.; Lane, David P.; Jackson, Robert C.; Glover, David M.; Fischer, Peter M. Journal of Medicinal Chemistry, 2010 , vol. 53, # 11 p. 4367 - 4378

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2wev
CK7
2c5p
1pxo
Cdk2/9 Inhibitor
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