[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acid
Modify Date: 2025-10-24 15:23:59
![[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acid Structure](https://image.chemsrc.com/caspic/053/50567-35-6.png)
[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acid structure
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Common Name | [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acid | ||
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| CAS Number | 50567-35-6 | Molecular Weight | 311.35700 | |
| Density | 1.379g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C13H17N3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acidMetamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1]. |
| Name | metamizole |
|---|---|
| Synonym | More Synonyms |
| Description | Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1]. |
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| Related Catalog | |
| In Vivo | Metamizo (Methamizole; 100 mg/kg; i.p.; once; male Swiss albino mice) causes hepatotoxicity as revealed by an increase in serum alanine aminotransferase (ALT) activity[1]. Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents[1]. Animal Model: Male Swiss albino mice (6 weeks old, 25-40 g)[1] Dosage: 100 mg/kg Administration: Intraperitoneal injection; once Result: Increased serum ALT level at 5 hours and the maximum serum ALT levels occurred at 5 hours. Animal Model: Male Swiss albino mice (6 weeks old, 25-40 g)[1] Dosage: 100 mg/kg Administration: Intraperitoneal injection; once Result: Induced reduction in hepatic glutathione (GSH) content in mice. |
| Density | 1.379g/cm3 |
|---|---|
| Molecular Formula | C13H17N3O4S |
| Molecular Weight | 311.35700 |
| Exact Mass | 311.09400 |
| PSA | 92.92000 |
| LogP | 1.84670 |
| Index of Refraction | 1.611 |
| InChIKey | LVWZTYCIRDMTEY-UHFFFAOYSA-N |
| SMILES | Cc1c(N(C)CS(=O)(=O)O)c(=O)n(-c2ccccc2)n1C |
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[(2,3-dihydro-1... CAS#:50567-35-6 |
| Literature: Winthrop Chem.Co. Patent: US2128512 , 1935 ; Full Text Show Details I.G.Farbenind. Patent: DE617237 , 1934 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 551 |
CAS#:76149-21-8
CAS#:76186-63-5
CAS#:73829-38-6| Metamizol |
| UNII-934T64RMNJ |
| Methamizole |
| Novamine sulfone |
| [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-methylamino]methanesulfonic acid |