5-hydroxyuracil

Modify Date: 2024-01-02 19:20:00

5-hydroxyuracil Structure
5-hydroxyuracil structure
Common Name 5-hydroxyuracil
CAS Number 496-76-4 Molecular Weight 128.086
Density 1.8±0.1 g/cm3 Boiling Point 534.5±53.0 °C at 760 mmHg
Molecular Formula C4H4N2O3 Melting Point 300ºC
MSDS Chinese USA Flash Point 277.0±30.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-hydroxyuracil
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 534.5±53.0 °C at 760 mmHg
Melting Point 300ºC
Molecular Formula C4H4N2O3
Molecular Weight 128.086
Flash Point 277.0±30.9 °C
Exact Mass 128.022186
PSA 85.95000
LogP -2.10
Appearance of Characters crystalline | light yellow
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.719
Water Solubility Soluble in DMSO (Sparingly), Methanol (Sparingly).

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles27

More Articles
Hydrolytic pathway of 5-fluorouracil in aqueous solutions for clinical use.

J. Pharm. Biomed. Anal. 98 , 446-62, (2014)

The purpose of the study was to investigate the degradation pathway of 5-fluorouracil (FU) in the situation of commercial formulations for clinical use, namely FU dissolved in sodium hydroxide (NaOH) ...

Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase.

Nucleic Acids Res. 32(17) , 5291-302, (2004)

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1), previously thought to be a backup enzyme for uracil-DNA glycosylase, has recently been shown to excise 5-hydroxyuracil (hoU), 5-h...

Base-promoted reaction of 5-hydroxyuracil derivatives with peroxyl radicals.

Org. Lett. 12(18) , 4130-3, (2010)

Addition of millimolar amounts of a weak base (pyridines) dramatically accelerates the reaction with peroxyl radicals of two biologically relevant uracil derivatives, 5-hydroxyuracil (HU) and 5-hydrox...

 Synonyms

Pyrimidinetriol
2,4,6-ThihydroxypyriMidine
pyrimidine-2,4,5-triol
Isobarbitursaeure
2,4,5-pyrimidinetriol
2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-
Isobarbituric Acid
2,4,5-Trihydroxypyrimidine,5-Hydroxyuracil,Isobarbituric acid
5-hydroxyuracil
2,4,5-Trihydroxypyrimidine
Fluorouracil impurity B
5-hydroxyisouracil
5-Hydroxypyrimidine-2,4(1H,3H)-dione
5-Hydroxy-2,4(1H,3H)-pyrimidinedione
TRIFLUOROACETIC ACID REAGENTPLUS
EINECS 207-829-9
MFCD00082987
Isobarbituric acid (VAN) (8CI)