(R)-Pantetheine

Modify Date: 2024-01-11 22:57:14

(R)-Pantetheine Structure
(R)-Pantetheine structure
Common Name (R)-Pantetheine
CAS Number 496-65-1 Molecular Weight 278.36800
Density 1.202g/cm3 Boiling Point 635ºC at 760mmHg
Molecular Formula C11H22N2O4S Melting Point N/A
MSDS N/A Flash Point 337.8ºC

 Use of (R)-Pantetheine


(R)-Pantetheine is the biosynthetic precursor to CoA.(R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA)[1].

 Names

Name pantetheine
Synonym More Synonyms

 (R)-Pantetheine Biological Activity

Description (R)-Pantetheine is the biosynthetic precursor to CoA.(R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA)[1].
Related Catalog
References

[1]. Rothmann M, et al. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. J Am Chem Soc. 2013 Apr 24;135(16):5962-5.

 Chemical & Physical Properties

Density 1.202g/cm3
Boiling Point 635ºC at 760mmHg
Molecular Formula C11H22N2O4S
Molecular Weight 278.36800
Flash Point 337.8ºC
Exact Mass 278.13000
PSA 137.46000
Vapour Pressure 8.53E-19mmHg at 25°C
Index of Refraction 1.526

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ES4316750
CHEMICAL NAME :
Butyramide, 2,4-dihydroxy-N-(2-((2-mercaptoethyl)carbamoyl)ethyl) -3,3-dimethyl-
CAS REGISTRY NUMBER :
496-65-1
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H22-N2-O4-S
MOLECULAR WEIGHT :
278.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
440 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957

 Safety Information

Hazard Codes T
Risk Phrases 25
Safety Phrases 45
RIDADR UN 2811 6.1 / PGIII

 Synonyms

(2R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)carbamoyl]ethyl]-3,3-dimethylbutyramide
Lactobacillusbulgaricusfactor
pantethine,Bis(N-pantothenylamidoethyl) disulfide
D-pantothenic acid-(2-mercapto-ethylamide)
D-N-pantothenylamidoethyl mercaptan
2,4-dihydroxy-3,3-dimethyl-N-[2-(2-sulfanylethylcarbamoyl)ethyl]butanamide
(R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutanamide
(R)-2,4-dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutyramide
Pantetheine