(R)-Pantetheine

Names

[ CAS No. ]:
496-65-1

[ Name ]:
(R)-Pantetheine

[Synonym ]:
(2R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)carbamoyl]ethyl]-3,3-dimethylbutyramide
Lactobacillusbulgaricusfactor
pantethine,Bis(N-pantothenylamidoethyl) disulfide
D-pantothenic acid-(2-mercapto-ethylamide)
D-N-pantothenylamidoethyl mercaptan
2,4-dihydroxy-3,3-dimethyl-N-[2-(2-sulfanylethylcarbamoyl)ethyl]butanamide
(R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutanamide
(R)-2,4-dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutyramide
Pantetheine

Biological Activity

[Description]:

(R)-Pantetheine is the biosynthetic precursor to CoA.(R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Rothmann M, et al. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. J Am Chem Soc. 2013 Apr 24;135(16):5962-5.

Chemical & Physical Properties

[ Density]:
1.202g/cm3

[ Boiling Point ]:
635ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₂₂N₂O₄S

[ Molecular Weight ]:
278.36800

[ Flash Point ]:
337.8ºC

[ Exact Mass ]:
278.13000

[ PSA ]:
137.46000

[ Vapour Pressure ]:
8.53E-19mmHg at 25°C

[ Index of Refraction ]:
1.526

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ES4316750

CHEMICAL NAME :: Butyramide, 2,4-dihydroxy-N-(2-((2-mercaptoethyl)carbamoyl)ethyl) -3,3-dimethyl-

CAS REGISTRY NUMBER :: 496-65-1

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H22-N2-O4-S

MOLECULAR WEIGHT :: 278.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 440 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.