NMDA receptor potentiator-1

Modify Date: 2024-04-05 18:45:19

NMDA receptor potentiator-1 Structure
NMDA receptor potentiator-1 structure
Common Name NMDA receptor potentiator-1
CAS Number 486427-18-3 Molecular Weight 467.94
Density N/A Boiling Point N/A
Molecular Formula C26H26ClNO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NMDA receptor potentiator-1


NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1].

 Names

Name NMDA receptor potentiator-1

 NMDA receptor potentiator-1 Biological Activity

Description NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1].
Related Catalog
Target

NR2C:4 μM (IC50)

NR2D:5 μM (IC50)

References

[1]. Stephen F. Traynelis, et al. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. Patent US8822462.

 Chemical & Physical Properties

Molecular Formula C26H26ClNO5
Molecular Weight 467.94
InChIKey KLJQHLQVCFUHRQ-UHFFFAOYSA-N
SMILES COc1ccc(OCC2c3cc(OC)c(OC)cc3CCN2C(=O)c2ccc(Cl)cc2)cc1
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