Neostenine

Modify Date: 2025-08-25 13:32:45

Neostenine structure	Common Name	Neostenine
	CAS Number	477953-07-4	Molecular Weight	277.40
	Density	1.1±0.1 g/cm3	Boiling Point	414.6±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₇NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	146.3±19.6 °C

Use of Neostenine

Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].

Name	(7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyldodecahydroazepi no[3,2,1-hi]furo[3,2-e]indol-10(2H)-one
Synonym	More Synonyms

Description	Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69(10):914-20. [2]. Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72(3):211-6.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

References

[1]. Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69(10):914-20.

[2]. Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72(3):211-6.

Density	1.1±0.1 g/cm3
Boiling Point	414.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₇NO₂
Molecular Weight	277.40
Flash Point	146.3±19.6 °C
Exact Mass	277.204193
PSA	29.54000
LogP	2.91
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.544

Hazard Codes	Xi

Azepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one, 8-ethyldodecahydro-11-methyl-, (7aR,8R,8aR,11S,11aR,11bS,11cR)-

(7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyldodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Neostenine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: NEOSTENINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.