Isotetrandrine

Modify Date: 2025-08-22 11:45:32

Isotetrandrine structure	Common Name	Isotetrandrine
	CAS Number	477-57-6	Molecular Weight	622.750
	Density	1.2±0.1 g/cm3	Boiling Point	710.5±60.0 °C at 760 mmHg
	Molecular Formula	C₃₈H₄₂N₂O₆	Melting Point	180-182ºC
	MSDS	N/A	Flash Point	175.8±30.1 °C

Use of Isotetrandrine

Isotetrandrine is a bioactive component in S. acutum[1].

Name	Isosinomenin A
Synonym	More Synonyms

Description	Isotetrandrine is a bioactive component in S. acutum[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Fangchi, derived from the rhizoma of S. acutum and the radix of S. tetrandra and S. acutum, has been widely used for the treatment of rheumatic arthritis[1].
References	[1]. Kim, Ji Hee et al. UHPLC Separation of Structurally Diverse Markers in Fangchi Species. (2013).

Density	1.2±0.1 g/cm3
Boiling Point	710.5±60.0 °C at 760 mmHg
Melting Point	180-182ºC
Molecular Formula	C₃₈H₄₂N₂O₆
Molecular Weight	622.750
Flash Point	175.8±30.1 °C
Exact Mass	622.304260
PSA	61.86000
LogP	3.55
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.586

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX7285000

CHEMICAL NAME :: 1-Isotetrandrine

CAS REGISTRY NUMBER :: 477-57-6

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C38-H42-N2-O6

MOLECULAR WEIGHT :: 622.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(5),176S,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,2413,1976

Hazard Codes	Xi

N-Methylcoclaurine

CAS#:1472-62-4

Isotetrandrine

CAS#:477-57-6

Literature: Bhakuni; Singh; Jain Tetrahedron, 1980 , vol. 36, # 14 p. 2149 - 2151

(+/-)-1-(4-hydr...

CAS#:17934-80-4

Isotetrandrine

CAS#:477-57-6

Literature: Bhakuni; Singh; Jain Tetrahedron, 1980 , vol. 36, # 14 p. 2149 - 2151

didehydro-N-met...

CAS#:66277-16-5

Isotetrandrine

CAS#:477-57-6

Literature: Bhakuni; Singh; Jain Tetrahedron, 1980 , vol. 36, # 14 p. 2149 - 2151

diazomethane

CAS#:186581-53-3

(1ξ,1'ξ)-6,6',1...

CAS#:38769-07-2

Isotetrandrine

CAS#:477-57-6

Literature: Kupchan; Liepa; Baxter; Hintz Journal of Organic Chemistry, 1973 , vol. 38, # 10 p. 1846 - 1852

diazomethane

CAS#:186581-53-3

Isotetrandrine

CAS#:477-57-6

Literature: Kugo Yakugaku Zasshi, 1959 , vol. 79, p. 322 Chem.Abstr., 1959 , p. 17161

diazomethane

CAS#:186581-53-3

Fangchinoline

CAS#:436-77-1

Isotetrandrine

CAS#:477-57-6

Literature: Mitscher,L.A. et al. Journal of the Chemical Society [Section] D: Chemical Communications, 1971 , p. 589 - 590

Precursor 5
CAS#:1472-62-4 N-Methylcoclaurine CAS#:17934-80-4 (+/-)-1-(4-hydr... CAS#:66277-16-5 didehydro-N-met... CAS#:186581-53-3 diazomethane
CAS#:436-77-1 Fangchinoline
DownStream 2
CAS#:3423-07-2 1α-(4-Hydroxybe... CAS#:479-37-8 16H-1,24:6,9-Di...

O,O'-Dimethylobamegine

isotetrandine

O-Methylberbamine

O,O'-Dimethylstepholine

6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman

Isosinomenine A

6,7,12,6'-tetramethoxy-2,2'-dimethyl-berbamane

1R,1'S isotetrandrine

1-isotetrandrine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Isotetrandrine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Isotetrandrine
Price: ￥3200.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Isotetrandrine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isosinomenin A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

Isotetrandrine suppliers

Price: ￥6500/5 mg

Reference only. check more Isotetrandrine price

Isotetrandrine

Use of Isotetrandrine

Names

Isotetrandrine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.