A-317491 structure
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Common Name | A-317491 | ||
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CAS Number | 475205-49-3 | Molecular Weight | 565.56900 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C33H27NO8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of A-317491A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors. IC50 value: Target: P2X2/3It is known that P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer patients for pain management. |
Name | 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid |
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Synonym | More Synonyms |
Description | A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors. IC50 value: Target: P2X2/3It is known that P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer patients for pain management. |
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Related Catalog | |
References |
Molecular Formula | C33H27NO8 |
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Molecular Weight | 565.56900 |
Exact Mass | 565.17400 |
PSA | 141.44000 |
LogP | 6.29350 |
Storage condition | -20°C |
cs-1250 |
A-317491 |