A-908292

Modify Date: 2025-08-24 17:00:30

A-908292 Structure
A-908292 structure
Common Name A-908292
CAS Number 903886-95-3 Molecular Weight 360.428
Density N/A Boiling Point N/A
Molecular Formula C18H20N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A-908292


A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).

 Names

Name A-908292

 A-908292 Biological Activity

Description A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
References 1. Nishiura Y, et al. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2498-2503. 2. Takagi H, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):256-263. 3. Waring JF, et al. J Pharmacol Exp Ther. 2008 Feb;324(2):507-16.

 Chemical & Physical Properties

Molecular Formula C18H20N2O4S
Molecular Weight 360.428
InChIKey OLMPAYQFDVALIH-ZDUSSCGKSA-N
SMILES COC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1
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