4'-Methylchrysoeriol

Modify Date: 2024-01-13 10:22:08

4'-Methylchrysoeriol Structure
4'-Methylchrysoeriol structure
Common Name 4'-Methylchrysoeriol
CAS Number 4712-12-3 Molecular Weight 314.28900
Density 1.402g/cm3 Boiling Point 538.3ºC at 760 mmHg
Molecular Formula C17H14O6 Melting Point N/A
MSDS N/A Flash Point 201.3ºC

 Use of 4'-Methylchrysoeriol


4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.

 Names

Name 2-(3,4-dimethoxyphenyl)-5,7-dihydroxychromen-4-one
Synonym More Synonyms

 4'-Methylchrysoeriol Biological Activity

Description 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
Related Catalog
Target

IC50: 19 nM ( human P450 1B1-dependent EROD)[1].

In Vitro 4'-Methylchrysoeriol (34DM57DHF) is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC50 of 19 nM for human P450 1B1-dependent EROD[1].
References

[1]. Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33.

 Chemical & Physical Properties

Density 1.402g/cm3
Boiling Point 538.3ºC at 760 mmHg
Molecular Formula C17H14O6
Molecular Weight 314.28900
Flash Point 201.3ºC
Exact Mass 314.07900
PSA 89.13000
LogP 2.88840
Index of Refraction 1.645

 Synthetic Route

 Synonyms

Kaempferol 3,4'-dimethyl ether
5,7-dihydroxy-3',4'-dimethoxyflavone
3',4'-dimethoxy-5,7-dihydroxyflavone
3'4'-dimethoxyluteolin
Kampferol-3,4'-dimethyl ether
luteolin-3',4'-dimethyl ether