2F5 epitope

Modify Date: 2024-04-07 20:55:07

2F5 epitope Structure
2F5 epitope structure
Common Name 2F5 epitope
CAS Number 470704-11-1 Molecular Weight 1616.81
Density N/A Boiling Point N/A
Molecular Formula C76H113N17O22 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2F5 epitope


2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].

 Names

Name 2F5 epitope

 2F5 epitope Biological Activity

Description 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].
Related Catalog
References

[1]. Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96.  

[2]. Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9.  

 Chemical & Physical Properties

Molecular Formula C76H113N17O22
Molecular Weight 1616.81