2F5 epitope

Names

[ CAS No. ]:
470704-11-1

[ Name ]:
2F5 epitope

Biological Activity

[Description]:

2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Others

[References]

[1]. Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96.  

[2]. Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9.  

Chemical & Physical Properties

[ Molecular Formula ]:
C76H113N17O22

[ Molecular Weight ]:
1616.81

Related Compounds