Thalifendine chloride

Modify Date: 2025-08-27 13:55:47

Thalifendine chloride Structure
Thalifendine chloride structure
 Common Name Thalifendine chloride
CAS Number 4668-19-3 Molecular Weight 357.79
Density N/A Boiling Point N/A
Molecular Formula C19H16ClNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalifendine chloride


Thalifendine chloride is a metabolite of Berberine (HY-N0716), with antiplasmodial and antiamoebic activities. Thalifendine chloride shows activity against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively[1][2].

 Names

Name Thalifendine chloride

 Thalifendine chloride Biological Activity

Description Thalifendine chloride is a metabolite of Berberine (HY-N0716), with antiplasmodial and antiamoebic activities. Thalifendine chloride shows activity against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively[1][2].
Related Catalog
Target

IC50: 7.91μM (P. falciparum), 116 μM (E. histolytica)[2]

References

[1]. Yi Li, et al. Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes. J Transl Med. 2011; 9: 62.

[2]. C W Wright, et al. In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. J Nat Prod. 2000 Dec;63(12):1638-40.

[3]. Ashish Kumar, et al. A new bisbenzylisoquinoline alkaloid isolated from Thalictrum foliolosum, as a potent inhibitor of DNA topoisomerase IB of Leishmania donovani. Fitoterapia. 2016 Mar;109:25-30.

 Chemical & Physical Properties

Molecular Formula C19H16ClNO4
Molecular Weight 357.79
InChIKey QKDAYMOWDPMRHC-UHFFFAOYSA-N
SMILES COc1c(O)ccc2cc3[n+](cc12)CCc1cc2c(cc1-3)OCO2.[Cl-]
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Thalifendine chloride suppliers

Thalifendine chloride price

Related Compounds: More...
Strontium chloride-Sr82
176302-73-1
Benzoyl chloride, 4-(1-methylpropyl)- (9CI)
86156-81-2
Benzenebutanoyl chloride, 3-chloro-
142018-93-7
cyclopentadienylmagnesium chloride
34766-85-3
Cyclohexanecarbonyl chloride, 2-(acetyloxy)-, trans- (9CI)
114250-36-1
dodecanoyl chloride,hydrofluoride
80584-96-9
Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)
89848-84-0
pentylmagnesium chloride
6393-56-2
anhydrobarakol chloride
28955-28-4
N-(4-(4-methyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)phenyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
1396880-90-2
3-(4-fluorophenyl)-6-(methylsulfanyl)-2H-[1,2,4]triazino[2,3-c]quinazolin-2-one
1798019-77-8
N-((4-(pyrrolidin-1-yl)pyrimidin-2-yl)methyl)acetamide
1797618-16-6
1-((2-(Dimethylamino)pyrimidin-4-yl)methyl)-3-(3-fluorophenyl)urea
1797252-80-2
5-(3,4-Difluorophenyl)pyrrolidin-3-ol hydrochloride
1423026-14-5
3-Amino-5,7-difluorobenzofuran-2-carboxylic acid
1823891-11-7
N-(cyanomethyl)-2-(cyclohexylsulfanyl)-5-nitrobenzamide
1797004-62-6
(1R)-1-(3-fluoro-4-methylphenyl)propan-1-ol
1270296-17-7
2-(3-Methoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine
1524831-57-9
3-Oxa-7-azabicyclo[3.3.1]nonane-9-carboxylic acid
1375473-72-5
Chemsrc provides Thalifendine chloride(CAS#:4668-19-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Thalifendine chloride are included as well.>> amp version: Thalifendine chloride

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved