valencene

Modify Date: 2024-01-03 17:54:54

valencene Structure
valencene structure
Common Name valencene
CAS Number 4630-07-3 Molecular Weight 204.35100
Density 0.89g/cm3 Boiling Point 270.5ºC at 760mmHg
Molecular Formula C15H24 Melting Point N/A
MSDS Chinese USA Flash Point 106ºC

 Use of valencene


Valencene is a sesquiterpene isolated from Cyperus rotundus, possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene is used to flavor foods and drinks[1][2][3].

 Names

Name (+)-valencene
Synonym More Synonyms

 valencene Biological Activity

Description Valencene is a sesquiterpene isolated from Cyperus rotundus, possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene is used to flavor foods and drinks[1][2][3].
Related Catalog
References

[1]. Yang IJ, et al. Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. Evid Based Complement Alternat Med. 2016;2016:9370893.

[2]. Frohwitter J, et al. Production of the sesquiterpene (+)-valencene by metabolically engineered Corynebacterium glutamicum. J Biotechnol. 2014 Dec 10;191:205-13.

[3]. Marques FM, et al. In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway. Inflammopharmacology. 2019 Apr;27(2):281-289.

 Chemical & Physical Properties

Density 0.89g/cm3
Boiling Point 270.5ºC at 760mmHg
Molecular Formula C15H24
Molecular Weight 204.35100
Flash Point 106ºC
Exact Mass 204.18800
LogP 4.72520
Index of Refraction n20/D 1.504(lit.)
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Safety Phrases S23-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

FEMA 3443
(3R,4aS,5R)-4a,5-Dimethyl-3-isopropenyl-1,2,3,4,4a,5,6,7-octahydronaphthalene
(1R,7R,8aS)-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)naphthalene
MFCD00075884
(R)-Valencene
Valencen
EINECS 225-047-6
VALENCE
VALENCENE 85
VALENCENE
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